Your medications. Your medical history. Your story.

I don't see Zepbound (tirzepatide) listed among your current medications, so this is general guidance rather than something tied to a dose you're already on.

In the clinical trial data, people on the highest approved dose (15 mg weekly) lost about 12% of their body weight on average over the trial period — that's a cumulative figure, not a flat monthly rate. Weight loss on Zepbound is also gradual and dose-dependent: it starts slow during the lower starter doses (2.5–5 mg) while your body adjusts, then tends to pick up once you reach your maintenance dose. Most people see the bulk of their loss over the first 6–12 months rather than a steady, predictable amount every month — so a "monthly" number isn't really how this medication works. Your prescriber would be the one tracking your specific trajectory against your starting weight and dose titration.

Side effects to expect, most commonly gastrointestinal: nausea, diarrhea, vomiting, constipation, stomach discomfort/pain, burping, and reflux (GERD). Other reported effects include injection site reactions, fatigue, hair loss, and hypersensitivity reactions (typically fever and rash). There are also more serious considerations: Zepbound caused thyroid C-cell tumors in rats, and it's unknown whether it does the same in humans, so it shouldn't be used with a personal or family history of medullary thyroid cancer or Multiple Endocrine Neoplasia type 2. It also hasn't been studied in people with a history of pancreatitis or severe gastrointestinal disease like severe gastroparesis, and it shouldn't be combined with Mounjaro or another GLP-1 medication.

I noticed you have a GLP-1 journey started recently — want me to check your record for anything relevant to flag with your prescriber before starting?